Dachshund family transcription factor
WebDACH2: dachshund family transcription factor 2 Summary. This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain ... WebJustin P. Kumar, in Current Topics in Developmental Biology, 2010 4.3 Dac: A transcription factor in search of a target. While a requirement for dac in eye specification and …
Dachshund family transcription factor
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WebApr 19, 2024 · Dachshund Whelping: The final stages of pregnancy. Whelping is the act of giving birth to puppies. Pregnancy is probably the easiest part of the entire ordeal if your … WebSymbol: DACH2: Name: dachshund family transcription factor 2: RGD ID: 1354112: HGNC Page: HGNC:16814: Description: Predicted to enable DNA-binding transcription ...
Webdachshund (dac) is a gene involved in the development of the arthropod compound eye which also plays a role in leg development. It is activated by the Distal-less (Dll) gene. … WebMar 21, 2024 · DACH1 (Dachshund Family Transcription Factor 1) is a Protein Coding gene. Diseases associated with DACH1 include Colobomatous Microphthalmia and Granular Cell Carcinoma.Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II general transcription …
WebThe present study investigated the role of dachshund family transcription factor 1 (DACH1) in IgAN and identified one of its binding microRNAs (miRNAs). The expression of … WebJan 21, 2011 · The cell fate determination factor Dachshund was cloned as a dominant inhibitor of the hyperactive epidermal growth factor receptor ellipse. The expression of Dachshund is lost in human breast cancer associated with poor prognosis. Breast tumor-initiating cells (TIC) may contribute to tumor progress …
WebDec 8, 2024 · The mouse dachshund gene is related to the Ski proto-oncogene and is expressed in eye and limb. These studies demonstrate a novel mechanism by which …
WebDachshunds are bred with the chondrodysplasia (dwarfism) gene, so it takes longer than normal for their legs to fully develop. Once they’re born, dachshund puppies start growing rapidly for the first 8 months or so. … great places to see in arizonaWebOct 4, 2024 · Transcription factors are DNA-binding proteins that play a key role in gene transcription. They are modular in structure and heterodimeric. Built within the transcription factor is a DNA-binding … floor mount cabinet slidesWebDec 13, 2024 · Dachshund family transcription factor 1 (DACH1) is a key component of the retinal determination gene network family that has been shown to be closely associated with organogenesis and tumorigenesis … great places to shop onlineWebINVOLVED IN development of primary female sexual characteristics (ortholog); ASSOCIATED WITH autistic disorder (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; amphetamine great places to seeGene structure . This protein coding gene has 760 amino acid protein, and an observed molecular weight of 52 kDa. Dachshund Family transcription factor 1 is encoded by DACH gene, who spans 400kDa and is encoded by 12 exons. This gene is located, in humans, in chromosome 13 (13q22). It encodes a chromatin-associated protein that associates with other DNA-binding transcription factors t… floor mount door lockWebDACH1, dachshund family transcription factor 1 Vertebrate Orthologs 4 Vertebrate Orthology Source. Alliance of Genome Resources. Human Ortholog DACH1, dachshund … floor mount bollardsWebIn breast cancer cells, DACH1 opposed SIX1 action, via transcriptional repression of common targets, including CCND1 and IL8 (interleukin 8) to inhibit cell proliferation and migration in vitro, as well as tumor growth and metastases in vivo ( Popov et al., 2010; Wu et al., 2008, 2006, 2007, 2003 ). floor mount double acting hinge