Ctr copper transporter family protein

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August undefined, 2024

WebMembers of the copper uptake transporter (CTR) family from yeast, plants, and mammals including human are required for cellular uptake of the essential metal copper. Based on biochemical data, CTRs have three … WebA different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes …

COPT5 copper transporter 5 [ Arabidopsis thaliana (thale cress) ]

WebOur research interests are primarily directed towards developing novel MS-based proteomics methods and applying them to the biomedical studies. LC-MS-based method … WebApr 11, 2024 · Arabidopsis copper transport protein COPT2 participates in the cross talk between iron deficiency responses and low-phosphate signaling. Plant Physiol., 162 (2013), ... Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol., 11 (2011), p. 69. View in Scopus Google Scholar chucky summary

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WebNational Center for Biotechnology Information WebFeb 1, 2024 · Furthermore, protein–protein interactions (PPI) analysis combined with validation experiments showed that the combination of AgNPs and domiphen could enhance the expression of copper transporter and inhibit nitrogen source metabolism. WebCopper uptake is regulated by CTR (copper transporter) family of proteins, which are highly conserved. High affinity copper uptake is facilitated by Ctr1 and Ctr3 in Saccharomyces cerevisiae and ... destiny 2 how to start red war campaign 2022

The copper transporter CTR1 provides an essential function

WebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... WebJul 24, 2024 · Naturally, this localization of the receptors requires the transport of monovalent copper from the plasma membrane via the cytoplasm to the apoproteins in the ER-Golgi membranes. The identity of the copper carriers involved in this task and their cellular routes are not yet completely known. destiny 2 how to switch difficultyWebApr 21, 2011 · The copper (Cu) transporter (COPT/Ctr) gene family has an important role in the maintenance of Cu homeostasis in different species. The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Here we report the … destiny 2 how to switch character

"WebApr 2, 2014 · Some pieces of evidence reported that Cu can be also taken up by other bivalent cations transporters, as the Natural Resistance Associated Macrophage Proteins (NRAMP), Zrt-and Irt-like proteins... " - Ctr copper transporter family protein

Ctr copper transporter family protein

Structure of the Ctr1 copper trans‘PORE’ter reveals novel …

Webthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights … WebApr 1, 2014 · Copper (Cu) is an essential micronutrient for all eukaryotes because it participates as a redox active cofactor in multiple biological processes, including mitochondrial respiration, photosynthesis, oxidative stress protection, and iron (Fe) transport. In eukaryotic cells, Cu transport toward the cytoplasm is mediated by the …

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WebGene name : SLC31A1. Family name : Copper transporter (Ctr) (TC 1.A.56) >>. SLC31A. Entry whose protein (s) existence is based on evidence at protein level. Show evidences. Annotations in this section apply to all the isoforms if not specified otherwise. WebOct 19, 2015 · These transport proteins are thought to have evolved from ‘half-transporters’ containing a single repeat via gene duplication and subsequent fusion 28. …

WebJan 5, 2024 · Enables copper ion transmembrane transporter activity. Involved in cellular copper ion homeostasis; copper ion transport; and regulation of heart rate. Located in plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of …

WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. … WebRecently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in …

WebDec 13, 2024 · Gene Summary Copper transporter 1A ( Ctr1A) encodes a plasma membrane protein that functions as a copper transporter. It is required to drive neuropeptide maturation during normal growth and development. [Date last reviewed: 2024-03-07] ( FlyBase Gene Snapshot ) All Summaries Gene Snapshot Gene Group Key …

WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69 destiny 2 how to start season of the seraphWebMar 1, 2003 · Recently it has been suggested that human Ctr1 (hCtr1) may act as a copper transporter in several tissues including the intestine. hCtr1 is a 190 amino acid protein and is predicted to have three transmembrane-spanning domains and exist in the plasma membrane as a homo-trimer. destiny 2 how to unlink accountWebJun 24, 2003 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … chucky surprise bagWebFeb 8, 2002 · This is the first report on the biochemical characterization of the human copper transporter hCtr1, which is important for understanding mechanisms for mammalian copper transport at the plasma membrane. The trace metal copper is an essential cofactor for a number of biological processes including mitochondrial oxidative … destiny 2 how to strand rocket flyWebDec 1, 2015 · The COPT/Ctr family belongs to a highly conserved Ctr-like Cu transporter family. Most COPT/Ctr transporters contain 3 TMDs: TMD1, TMD2, and TMD3. The N terminus of most COPT/Ctr transporters includes methionine motifs involved in Cu binding that is important for facilitated import (Beaudoin et al., 2011). chucky superflixWebNov 1, 2006 · CTR1 belongs to the CTR (or SLC31A) family that includes CTR1/2 and P-type copper transporting ATPases (ATP7A and B). It is a 23-kDa channel-like transporter which has a unique pore for the transport of copper and three trans-membranes domains that oligomerize to form a functional trimer [85]. destiny 2 how to start battlegroundsWebStudies were conducted to determine distribution of the copper transporter, Ctr1, a transmembrane protein responsible for cellular copper uptake, in adult mice and in … chucky svg black and white