WebFeb 16, 2024 · In an unusual move, technology giant IBM has in effect ‘spun off’ its eDiscovery suite, along with other software related to unstructured data analysis, to a new company called Breakwater.. Breakwater has taken on IBM StoredIQ, IBM StoredIQ for Legal, IBM StoredIQ InstaScan, and the IBM Atlas suite of products.Through a … WebFeb 1, 2024 · Methods: BREAKWATER is an open-label, global, multicenter, randomized, phase 3 study with a safety lead-in (SLI). Approximately 60 and 870 pts will be enrolled in the SLI and phase 3 parts of the ...
Cetuximab monotherapy and cetuximab plus irinotecan in
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BREAKWATER - Victorian Cancer Trials Link
WebCOLORECTAL: METASTATIC: 1ST LINE: BRAF MT: BREAKWATER. An open-label, multicenter, randomized Phase 3 study of first-line encorafenib plus cetuximab with or … WebJun 2, 2024 · TPS3634 Background: Among patients with MSI-H/dMMR CRC, BRAF mutations occur in approximately 30%. MSI-H/dMMR and BRAF mutations are both associated with poor prognosis; in patients who have both biomarkers, poor prognosis is thought to be driven by the BRAF mutation. Pembrolizumab is indicated for the treatment … WebJul 22, 2004 · Background: The epidermal growth factor receptor (EGFR), which participates in signaling pathways that are deregulated in cancer cells, commonly appears on colorectal-cancer cells. Cetuximab is a monoclonal antibody that specifically blocks the EGFR. We compared the efficacy of cetuximab in combination with irinotecan with that of cetuximab … gudrun theis